Mouse Anti- Cartilage Oligomeric Matrix Protein Antibody (16B5)


Product number #10150

Affinity purified mouse monoclonal Anti-Cartilage Oligomeric Matrix Protein (COMP) antibody clone 16B5 in PBS, sterile filtered (0.2 µm)


20220412_094637
Size and Price

100µg / 0.1mL         249 €

1 mg / 1mL       1,200 €

For bulk orders, please contact info@vacara.se to request a quote.

 Price is excluding shipping cost. The shipping cost will be added on.


16B5

 






16B5 binds to COMP (hCOMP, recombinant human COMP) but not to denatured COMP. Binding was determined in bead-based flow immunoassay as median fluorescence intensity (MFI). Bovine serum albumin (BSA) was used as the negative control.


Description


Affinity purified mouse monoclonal Anti- Cartilage Oligomeric Matrix Protein (COMP) antibody clone 16B5 in PBS, sterile filtered (0.2 µm). The 16B5 antibody binds to the coiled-coil domain or pentamer COMP1. This antibody has been used in applications including immunohistochemistry (IHC)1 and ELISA1,2.

Target with alternative names

Cartilage Oligomeric Matrix Protein; COMP;
UniProt Q9R0G6

Immunogen

Rat Cartilage Oligomeric Matrix Protein1

Species reactivity

Rat, mouse, human1

Isotype

Mouse IgG1, κ

Concentration

1mg/ml

Sizes available

100µg and 1mg

Supplied in

PBS

Storage

Centrifuge briefly prior to opening the vial. Store at +4°C short term (1-2 weeks). Aliquot and store at ‑20°C long term. Avoid repeated freeze/thaw cycles.

Recommended dilution

It is recommended the user determines the optimal dilution for their application. The typical starting working dilutions are: IHC 1:100, ELISA 1:200-1:500.

 

For Research Use Only. Not for use in diagnostic procedures.
Not for resale without express authorization.

 

References

1.       Geng H, Nandakumar KS, Pramhed A, Aspberg A, Mattsson R, Holmdahl R. Cartilage oligomeric matrix protein specific antibodies are pathogenic. Arthritis Res Ther. 2012 Aug 20;14(4):R191. PMID: 22906101.

2.       Geng H, Nandakumar KS, Xiong L, Jie R, Dong J, Holmdahl R. Incomplete B cell tolerance to cartilage oligomeric matrix protein in mice. Arthritis Rheum. 2013 Sep;65(9):2301-9. PMID: 23754310.

Documents

Vacara_16B5.pdf