Mouse Anti- Cartilage Oligomeric Matrix Protein Antibody (15A11)
Product number #10140
Affinity purified mouse monoclonal Anti-Cartilage Oligomeric Matrix Protein (COMP) antibody clone 15A11 in PBS, sterile filtered (0.2 µm)
100 µg / 0.1mL 249 €
1 mg / 1mL 1,200 €
For bulk orders, please contact info@vacara.se to request a quote.
Price is excluding shipping cost. The shipping cost will be added on.
The mouse monoclonal anti- Cartilage Oligomeric Matrix Protein (COMP) antibody clone 15A11 binds to the fourth EGF (epithelial growth factor) -like domain of murine COMP, comprising residues 232–252, called the P6 epitope. Binding to recombinant human COMP (Product number #10020) was determined in enzyme linked immunosorbent assay (ELISA) as absorbance at 405nm.
Description
Affinity purified mouse monoclonal anti- Cartilage Oligomeric Matrix Protein (COMP) antibody clone 15A11 in PBS, sterile filtered (0,2 µm). The 15A11 antibody binds to the fourth EGF (epithelial growth factor) like domain of murine COMP, comprising residues 232–252, called the P6 epitope1. This antibody has been used in applications including immunohistochemistry (IHC)1, and in vivo functional assays2.
Target with alternative names
Cartilage Oligomeric Matrix Protein; COMP;
UniProt Q9R0G6
Rat Cartilage Oligomeric
Matrix Protein1
Species reactivity
Rat, mouse, human1
Isotype
Mouse IgG1, κ
Concentration
1 mg/ml
Sizes available
100 µg / 0.1 mL and 1 mg / 1 mL
Supplied in
PBS
Storage
Centrifuge briefly prior to
opening the vial. Store at +4°C short term (1-2 weeks). Aliquot and store at ‑20°C
long term. Avoid repeated freeze/thaw cycles.
It is recommended the user determines the optimal dilution for their application. The typical starting working dilutions are: IHC 1:100, ELISA 1:200-1:500.
For Research
Use Only. Not for use in diagnostic procedures.
Not for resale
without express authorization.
References
1. Geng H, Nandakumar KS, Pramhed A, Aspberg A, Mattsson R, Holmdahl R. Cartilage oligomeric matrix protein specific antibodies are pathogenic. Arthritis Res Ther. 2012 Aug 20;14(4):R191. PMID: 22906101.
2. Li Y, Tong D, Liang P, Lönnblom E, Viljanen J, Xu B, Nandakumar KS, Holmdahl R. Cartilage-binding antibodies initiate joint inflammation and promote chronic erosive arthritis. Arthritis Res Ther. 2020 May 24;22(1):120. PMID: 32448385.
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